Conclusions: In the evaluation of spinal cord damage in early cervical spondylosis, mean DK and RMSD values in the spinal cord may be highly sensitive indicators of microstructural change and damage. ADC was also higher in compressed cords, but this difference was not statistically significant. Results: FA and mean DK values were significantly lower and RMSD was significantly higher ( P = 0.0060, 0.0020 and 0.0062, respectively Mann-Whitney U test with the Bonferroni correction) in compressed spinal cords than in uncompressed cords. Fractional anisotropy (FA), apparent diffusion coefficient (ADC), RMSD and mean DK values were calculated and compared between compressed and uncompressed spinal cords.

After conventional magnetic resonance (MR) imaging, diffusion tensor and q-space image data were acquired using 3-T MR imaging.

Methods: We studied 50 consecutive patients at our institution (22 male, 28 female mean age 58 years age range 20-86 years) who had clinical signs and symptoms suggestive of early clinical stage cervical myelopathy. Abstract: Objectives: To investigate the use of root mean square displacement (RMSD) and mean diffusional kurtosis (DK) metrics of q-space imaging data to estimate spinal cord compression in patients with early cervical spondylosis.

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